What does the «Use Separate Process» option mean in the «Cron (Scheduled Tasks)» settings block?

Magento\Cron\Observer\ProcessCronQueueObserver::execute()

Conclusion

If the «Use Separate Process» option is enabled for a Cron group, then the group’s jobs will be executed in a separate process of the operating system.
Usually, Magento 2 contains only 2 Cron groups: default and index, but third-party extensions can add extra Cron groups.

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